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Symposia

The 33rd International KOGO Annual Conference


Unraveling Genomes, Empowering Futures


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(Click on the session name to view the detailed program)
2024.09.05. (Thu)
09:00-10:30(90')
 

Hall A
Session 1. Genome Editing
Functional Genomics in CRISPR for Personalized Therapy
 
CRISPR holds immense promise for personalized therapy, offering the potential to tailor treatments to individual genetic profiles, thus revolutionizing the approach to treating a myriad of diseases. In this session, we will hear recent advances in genome-editing technologies and their applications ranging from genetic diseases to cancer. Also, we will discuss functional (transcriptome) readout of CRISPR, which invovles analyzing changes in gene expression induced by gene-editing. Combining CRISPR with omics provides multi-dimensional data, offering a more comprehensive understanding of disease mechanisms.

Organizer: Byungjin Hwang (Yonsei University College of Medicine)
Chair: Yeun-Jun Chung(The Catholic University of Korea), Seung Hwan Lee (Chung-Ang University)
09:00-09:20(20') Targeted In Vivo Gene Integration of Secretion-Enabled GLP-1 receptor agonist Alleviates Diet-induced Obesity and Pre-diabetes Keiichiro Suzuki
(Institute for Advanced Co-Creation Studies, Osaka University)
09:20-09:40(20') Saturation Resistance Profiling of EGFR Variants against Tyrosine kinase Inhibitors using Prime Editing Hyongbum Henry Kim
(Yonsei University College of Medicine)
09:40-10:00(20') Writing and Reading Genomes:
Functional Genomics Study with CRISPR and Single-cell Sequencing		 Heon Seok Kim
(Hanyang University)
10:00-10:20(20') Precise Genome Engineering: from Nucleus to Mitochondria Kayeong Lim
(Korea Institute of Science and Technology)
09:00-10:30(90')
 

Hall B
Session 2. Plant (+Marine)
Systematic Plant Exploration: Integrating Genomics, Transcriptomics, and Proteomics
 
The advancement of omics technologies has significantly contributed to deepening our understanding of plant biology and enhancing applications in agriculture. Through the integration of genomic, transcriptomic, and proteomic approaches, researchers have uncovered intricate plant mechanisms and developed innovative solutions to improve crop resilience and productivity. In this session, our aim is to introduce the latest research trends in plant omics biology and discuss how this systemic approach promises to propel both fundamental plant science and its practical applications forward.

Organizer: Hye Ryun Woo (DGIST)
Chair: Ik-Young Choi (Kangwon National University), Hye Ryun Woo (DGIST)
09:00-09:20(20') Border Competition of Sugar between Rice and Rhizoctonia solani Yuan Hu Xuan
(Nankai University)
09:20-09:40(20') Identification of the Molecular Barrier for Crop Regeneration Hyo-Jun Lee
(KRIBB)
09:40-10:00(20') How to Cope with Multiple Enemies: Metabolomic and Transcriptomic Approaches to Assess Plant Optimal Defenses Against Multiple Herbivores Youngsung Joo
(Seoul National University)
10:00-10:20(20') A Single-cell Step Forward towards Understanding Phloem Identity and Function Ji-Yun Kim
(Sungkyunkwan University)
11:00-11:40(40')
* Plenary Lecture Ⅰ

Chair: Yeon-Su Lee (National Cancer Center, Korea)

UK Biobank: Scale, Depth, Duration … but, Most Importantly, Accessibility

Sir Rory Collins (Oxford University)
11:40-12:20(40')
* Unbong Kang Hyen Sam Award Lecture

Chair: Changwon Kang (KAIST)

TBA

TBA
12:20-13:20(60')
 

Hall A

 Luncheon Seminar 1 Geninus
Advances in Spatial Transcriptomics Technology from Microscale to Nanoscale
Siyoung Lee (Geninus Inc.)
12:20-13:20(60')
Hall B
 Luncheon Seminar 2 MDxK
12:20-12:50(30')
A New Era in Short-Read Sequencing with SBB
Doohyun Park (PacBio APAC)
12:50-13:20(30')
Advancing Tumor Transcriptome Analysis through Long-Read Sequencing
Charny Park (National Cancer Center, Korea)
13:20-14:50(90')
 

Hall A
Session 3. Single Cell Genomics
Atlas-scale Single Cell Studies
 
This session delves into cutting-edge research mapping cellular diversity and dynamics across various human tissues and developmental stages. Presentations will cover groundbreaking findings, including the clonal dynamics of the human forebrain, the cellular and molecular mechanisms of alveolar development in the human fetal lung, heritable modes of fate decisions in gastruloids, and the transcriptomic landscape of human glomerular diseases. This session promises to provide invaluable insights into the complex cellular interactions and genetic influences shaping human health and disease.

Organizer: Jihwan Park (GIST)
Chair: Jong-Il Kim (Seoul National University), Chang Ho Sohn (Yonsei University)
13:20-13:40(20') Cell-type-resolved Mosaicism Reveals Clonal Dynamics of the Human Forebrain Changuk Chung
(University of California San Diego)
13:40-14:00(20') Human Fetal Lung Cell Atlas and Organoid Modeling: Unveiling Cellular and Molecular Mechanisms of Alveolar Development Kyungtae Lim
(Korea University)
14:00-14:20(20') Molecular Recording Reveals Heritable Modes of Fate Decisions in Gastruloids Junhong Choi
(Memorial Sloan Kettering Cancer Center)
14:20-14:40(20') Single-nucleus Transcriptomic Landscape of Human Glomerular Diseases Sehoon Park
(Seoul National University Hospital)
13:20-14:50(90')
 

Hall B
Session 4. Microbiome
Multi-omics Approaches to Microbiome Exploration
 
This session will introduce the latest research findings derived from multi-omics approaches in microbiome research. These approaches involve the integrated analysis of various types of biological data to gain a comprehensive understanding of the structure and function of microbial communities in the context of various diseases. By providing insights into the complex interactions between the microbiome and the host, these studies uncover the mechanisms by which microbial communities influence diseases, paving the way for innovative diagnostic and therapeutic strategies.

Organizer: Eun-Jin Lee (Korea University)
Chair: In-Jin Jang (Seoul National University), Yong-Joon Cho (Kangwon National University)
13:20-13:50(30') Understanding of Human Microbiome using Multi-Omics from an Ecological Perspective Bong-Soo Kim
(Hallym University)
13:50-14:20(30') Metagenomic and Metabolomic Analyses Reveal Distinct Stage-specific Phenotypes of the Gut Microbiota in Colorectal Cancer Takuji Yamada
(Tokyo Institute of Technology)
14:20-14:50(30') Harnessing the Gut Microbiome for Medical Science Ji-Won Huh
(Chungnam National University)
13:20-15:20(120')
 

Conference Room 1&2
Workshop
UK Biobank, a Unique Global Platform for Genomic Discovery Science
 
UK Biobank is a large-scale prospective study and research resource with de-identified genetic, proteomic, metabolomic, imaging, lifestyle, environmental, and health data from 500,000 UK adults. It is the most comprehensive and widely-used dataset of its kind, accessible globally to health researchers in academic, commercial, government, or charitable settings.
Over 30,000 researchers from 90+ countries use UK Biobank data, resulting in over 10,000 peer-reviewed publications. To support its growth and global accessibility, UK Biobank have launched a cloud-based Research Analysis Platform and aims to further democratize access through the Global Researcher Access Fund.
This 2.5 hour workshop will cover registering and accessing the resource, an overview of the data available including genomic datasets, and an introduction to the UK Biobank Research Analysis cloud-based Platform.

Organizer: Education Committee

Chair: Naomi Allen (UK Biobank)
13:20-13:25(5') UK Biobank Workshop Introduction
Naomi Allen
(UK Biobank)
13:25-13:50(25') Overview of Data in the UK Biobank Resource 
Jelena Besevic
(UK Biobank)
13:50-14:00(10') Registering and Accessing UK Biobank
Jelena Besevic
(UK Biobank)
14:00-14:15(15') Introduction to the UK Biobank Research Analysis Platform UK Biobank Data Analyst team
14:15-14:25(10') Harnessing the Power of UK Biobank Seunggeun Lee
(Seoul National University)
14:25-14:50(25') Powerful Analysis in the UK Biobank Research Analysis Platform UK Biobank Data Analyst team 
14:50-15:20(30') Q&A and Discussion All
15:20-16:00(40')
* Plenary Lecture Ⅱ

Chair: Yeul Hong Kim (Yuhan Corporation)

Identifying Functional Non-coding Variants at Multiple Biological Scales

Sridhar Hannenhalli (National Cancer Institute)
16:00-17:30(90')
 

Hall A
Session 5. Epigenetics
Epigenetics: New Rising Dimensions in Genomic Discovery
 
Explore the frontier of genomics in "New Rising Dimensions in Genomic Discovery." This session unveils cutting-edge research on the 3D organization of our genetic blueprint and its impact on cellular function. Our speakers will present groundbreaking work on long noncoding RNAs in genome regulation, computational methods for chromatin structure analysis, the interplay between metabolism and cancer epigenetics, and the role of nuclear bodies in genome interactions. Join us to discover how these advances are reshaping our understanding of genomics and opening new avenues for medical innovation. This session offers a compelling glimpse into the multidimensional nature of the genome, relevant for researchers, students, and anyone fascinated by the complexity of life's code.

Organizer: Hyunho Han (Yonsei University College of Medicine)
Chair: Hyoung-Pyo Kim (Yonsei University College of Medicine), Hyunho Han (Yonsei University College of Medicine)
16:00-16:20(20') Regulation of 3D Genome Architecture by Long Noncoding RNAs Hyun Jung Oh
(Yonsei University)
16:20-16:40(20') A Computational Method to Reconstruct 3D Chromatin Polymer Coordinates in Single Cells Minhee Park
(KAIST)
16:40-17:00(20') Metabolic Environment Shape Cancer Metabolism and Epigenome Min-Sik Lee
(POSTECH)
17:00-17:20(20') MAZ Mediates the Interplay between the 3D Genome and Nuclear Bodies Inkyung Jung
(KAIST)
16:00-17:30(90')
 

Hall B
Session 6. Advances in Omics Technology
Advances in Omics Technology
 
This session highlights groundbreaking advancements in proteomics, proteogenomics, single-cell analysis, and AI-enhanced genomic data interpretation. Our speakers will present pioneering work on biomarker discovery, clinical diagnostics, comprehensive cellular function analysis, and enhanced genomic data utility through AI. Somalogic will illustrate how SomaScan technology aids in biomarker discovery and clinical application. Bertis Inc. will discuss the integration of proteomic and genomic data for personalized medicine and advanced research. Illumina will showcase their AI-powered software that streamlines genome interpretation, accelerating research and clinical decision-making. Join us to uncover how these technologies are transforming research and clinical practices, providing new insights into biological systems, and paving the way for novel diagnostic and therapeutic approaches.

Organizer: Planning Committee
Chair: Se-Hoon Lee (Samsung Medical Center), Hyun Seok Kim (Yonsei University)
16:00-16:30(30') SomaScan Proteomics: From Biomarker Discovery to Clinical Diagnosis
Bellbull Kim
(Somalogic)
16:30-17:00(30') The Dawning of a Proteomics Era: Proteogenomics, Single-cell Analysis, and Beyond Sunghyun Huh
(Bertis Inc.)
17:00-17:30(30') Streamlines Genome Interpretation to Improve the Utility of Genomic Data with Illumina Connected Software through AI Jeongmin Kim
(Illumina)
16:00-17:30(90')
 

Conference Room 1&2
Satellite Session 1. KNIH
Cohort-Based Multimodal Data in AI: Case Studies and Insights
 
This session will provide an overview of healthcare data curated by the National Institutes of Health, with a particular focus on advanced AI-driven research applications. It will explore the use of AI in analyzing omics data and brain imaging from the Biobank Innovation for Chronic Cerebrovascular Disease With Alzheimer's Disease Study (BICWALZS). Additionally, the session will examine integrative research examples involving genetic data and brain imaging data from the Korean Genome and Epidemiology Study (KoGES). The session will also share analytical pipelines and use cases for building data for AI learning.

Organizer: Sang Cheol Kim (National Institute of Health)
Chair: Sang Cheol Kim (National Institute of Health)
16:00-16:20(20') Cognitive Impairment Prediction Model using Korean Reference Multimodal Data Sang Cheol Kim 
(National Institute of Health)
16:20-16:40(20') Genomic & Proteomic Research of the Innovative Biobanking Consortium for Chronic Cerebrovascular Disease: findings from BICWALZS Hyun Woong Roh
(Ajou University School of Medicine)
16:40-17:00(20') Cytokines and sc-RNA seq Integration in Discovering Biomarkers of COVID-19 Symptom Manifestation Sun Shim Choi
(Kangwon National University)
17:00-17:20(20') Development of Multi-omics and AI Pipelines with WDS and Docker Hyungyong Kim
(Insilicogen, Inc.)
2024.09.06. (Fri)
09:00-10:30(90')
 

Hall A
Session 7. Bioinformatics & Systems Biology
Translating Complex Life Sciences Data into Clinical Insights with Bioinformatics
 
This session on Bioinformatics and Systems Biology will explore the intricate interplay between genomic variations and disease mechanisms. Presentations will cover the influence of somatic cancer driver mutations on microglial expansion in Alzheimer's disease, the landscape of somatic pan-mosaicism through genomic and epigenomic analyses, and cutting-edge computational workflows for genome analysis and variant discovery, highlighting the common theme of understanding genetic influences on disease.

Organizer: Seunghee Hong (Yonsei University)
Chair: Sanghyuk Lee(Ewha Womans University), Seunghee Hong(Yonsei University)
09:00-09:30(30') Somatic Cancer Driver Mutations Induce Microglial Clonal Expansion in Alzheimer’s Disease Alice Lee
(Harvard Medical School)
09:30-09:50(20') Genomic and Epigenomic Analyses of Clones Reveal the Landscape of Somatic Pan-mosaicism in Human Young Seok Ju
(KAIST)
09:50-10:10(20') Diving into Computational Workflows in Genome Analysis and Variant Discovery Young-suk Lee
(KAIST)
10:10-10:30(20') Rare Variant Association Analysis Seunggeun Lee
(Seoul National University)
09:00-10:30(90')
 

Hall B
Session 8. Young Scientists' Session
Young Scientists' Session
 
This session provides a platform for emerging researchers to showcase their innovative work in genomics. It will feature groundbreaking research, from genetic mapping to personalized medicine, conducted by the brightest young minds in science. Attendees will gain insights into the latest techniques fostering a collaborative environment that encourages networking, knowledge sharing, and inspiration among the next generation of scientists.

Chair: Tae-Min Kim (The Catholic University of Korea), Sungho Park (UNIST)
09:00-09:20(20') A Cross-tissue Transcriptome Atlas of Human Diseases Seongryong Kim
(KAIST)
09:20-09:40(20') Distant Origin of Glioblastoma Recurrence: Neural Stem Cells in the Subventricular Zone Serve as a Source of Tumor Reconstruction after Primary Resection Xue Li
(Seoul National University Hospital)
09:40-10:00(20') Large-scale Genomic Analyses Identify Distinct Polygenic Adaptations for Skin Color in East Asians and Europeans Joong-Gon Shin
(LG Household & Healthcare)
10:00-10:20(20') Early Immune Remodeling Steers Clinical Response to First Line Chemoimmunotherapy in Advanced Gastric Cancer Minae An
(Samsung Medical Center)
09:00-10:30(90')
 

Conference Room 1&2
Satellite Session 2
Genome Research and Applications using the Korea Biobank Array
(한국인칩을 이용한 유전체 연구 및 활용)
 
This session will explore the latest advancements in Korean genome research facilitated by the Korea Biobank Array, with a focus on its applications in pharmacogenomics and disease genomics. Presentations will cover key topics such as insights gained from large-scale genome studies using the Korea Biobank Array, along with practical research experiences. Additionally, the session will highlight the development of genome research infrastructures aimed at enhancing the utility and impact of Korean genome research. This session promises to provide valuable perspectives on leveraging Korean genomic data to improve health outcomes in Korea.

Organizer: Bong Jo Kim (National Institute of Health)
Chair: Jae Pil Jeon (National Institute of Health)
09:00-09:25(25') Research Experiences using the Korean-Chip Combined with Clinical Data
Je Hyun Seo
(Veterans Health Service Medical Center)
09:25-09:50(25') Enhanced Risk Stratification of Metabolic Diseases by Analyzing Genomic Data via the Korea Biobank Array
Young Jin Kim
(National Institute of Health)
09:50-10:15(25') Advances in Preemptive PGx Testing: Insights from Genomic Sequencing and Major National Genomic Project Databases
Chan Hee Park
(Theragen Bio)
10:15-10:30(15') Infrastructures for Enhancing Utility of Korean Genome Research
Bong Jo Kim
(National Institute of Health)
10:50-11:30(40')
* Plenary Lecture Ⅲ

Chair: Wonshik Han (Seoul National University)

FinnGen, An Example of a Northern European Large Scale Biobank Study

Aarno Palotie (University of Helsinki)
11:30-12:15(45')

Conference Room 1&2
Korean Pangenome Project: Recruiting voluntary Korean participants
12:30-13:30(60')
 

Hall A

 Luncheon Seminar 3 10x Genomics - DAON BioSciences
Spatial Transcriptomics to Unravel the Tumor Microenvironment of Solid Tumors and Revolutionize Cancer Therapy
Kwon Joong Na (SNUH)
12:30-13:30(60')
 

Hall A

 Luncheon Seminar 4 MobiDrop - Diagenex
Mammalian and Microbial Single-cell Sequencing Solutions
Yanquan Luo (MobiDrop Co., Ltd.)
13:30-15:00(90')
 

Hall A
Session 9. Common Complex Disease
Harmonizing Information for Unraveling Common Complex Diseases
 
The session aims to uncover the causes of complex diseases, share findings from integrating and analyzing large-scale data, and highlight the importance of collaborative research and advanced computational methods in understanding these conditions.

Organizer: Sang Cheol Kim, Young Jin Kim (National Institute of Health)
Chair: Sangsoo Kim (Soongsil University), Kwoneel Kim (Kyung Hee University)
13:30-14:00(30') Plasma Proteomic Signatures of Adiposity and Type 2 Diabetes
Sim Xueling
(Singapore National University)
14:00-14:20(20') Meta-analysis of Repeat Genome-wide Association Study (MERG): a Powerful Method for Genome-wide Association Study with a Longitudinal Follow-up

Seong Beom Cho

(Gachon University)
14:20-14:40(20') COVID-eQTL: Genetic Determination of COVID-19 Severity Murim Choi
(Seoul National University)
14:40-15:00(20') Uncovering Genetic Architecture of Complex Traits using Multi-trait Community Detection Approaches Buhm Han
(Seoul National University)
13:30-15:00(90')
 

Hall B
Session 10. Genomics & Informatics Symposium
Exploring Genomic Insights: Analyzing Data from Emerging Platforms
 
Emerging platforms for high-throughput sequencing have been revolutionizing genomic studies. In this session, such emerging platforms and their genomic insights will be discussed, including single cell sequencing, spatial transcriptomics, and long-read sequencing. Three speakers will provide the application of cutting-edge sequencing technologies to investigate cell-cell interactions, tissue microenvironments, and novel transcriptomic mechanisms.

Organizer: Editorial Committee - Junil Kim (Soongsil University)
Chair: Taesung Park (Seoul National University), Junil Kim (Soongsil University)
13:30-14:00(30') Studying the Influence of Cell-cell Contact from Various Spatial Transcriptomics Datasets Kyoung-Jae Won
(Cedars-Sinai Medical Center)
14:00-14:30(30') Long-Read Sequencing to Discover Genomic and Transcriptomic Dark Matter Jun Kim
(Chungnam National University)
14:30-15:00(30') Understanding the Complex Microenvironment of Neurodegenerative Diseases through Spatially Resolved Transcriptomics Sungwoo Bae
(Portrai)
13:30-15:00(90')
 

Conference Room 1&2
Satellite Session 3. Microsoft
Innovation of Genomics with Microsoft Technologies
 
Join us to discover the cutting-edge technology of Microsoft Azure HPC to accelerate and revolutionize genomic research. You can explore how Microsoft AI is being utilized in healthcare in the era of generative AI, showcasing real-world applications and breakthroughs.

Organizer: Jongsu Jeon (Microsoft)
Chair: Anne Shin (Microsoft)
13:30-14:15(45') Introduction to Azure HPC for Genomics
Sooyoung Moon
(Microsoft)
14:15-15:00(45') How Microsoft AI approaches Genomics
HyeonYeong Seo
(Microsoft)
15:20-16:00(40')
* Plenary Lecture Ⅳ

Chair: Tae-You Kim (Seoul National University)

RNA Regulation: Lessons from Viruses and RNA Therapeutics

V. Narry Kim (Seoul National University)
16:00-17:30(90')
 

Hall A
Session 11. Stem Cell Genomics
Stem Cell Genomics Reshapes Our Understanding
 
This Stem Cell session showcases cutting-edge research linking genomics and stem cell biology. Talks will explore stem cells in gastrointestinal cancer, innovative therapies for neurological disorders, chromatin dynamics in hematopoietic development, and cell therapy for neurodegenerative diseases. This diverse lineup highlights how genomic insights are transforming our understanding of stem cells and their applications in oncology, neurology, and regenerative medicine, promising significant advances in disease treatment and cellular therapies.

Organizer: Jungmin Choi (Korea University College of Medicine)
Chair: Jong Hoon Park (Sookmyung Women’s University), Hanseul Yang (KAIST)
16:00-16:25(25') Deciphering Stem Cell Roles in Driving Gastrointestinal Cancer Nick Barker
(A*STAR Institute of Molecular and Cell Biology)
16:25-16:50(25') Stem Cells and Cell Reprogramming: Revolutionizing Treatments for Neurological Disorders Jongpil Kim
(Dongkuk University)
16:50-17:15(25') Nuclear Architecture and Chromatin Dynamics in Hematopoietic Cell Development Hyeji Cha
(Dankook University)
17:15-17:30(15') Cell Therapy Approach for Neurodegenerative Disease Yongjin Yoo
(Korea University College of Medicine)
16:00-17:30(90')
 

Hall B
Session 12. Animal Genome (+Marine)
Revealing the Genome of Every Animal: Where Are We Now?
 
This session explores diverse areas of biological research, utilizing advanced techniques and model organisms to highlight fundamental biological processes such as aging and hematopoiesis, and conservation efforts for iconic species such as the giant panda. It will present cutting-edge research in genomics, single-cell transcriptomics, and model organism studies. These topics demonstrate the interdisciplinary nature of modern biological research and its broad implications for understanding fundamental biological processes, conservation efforts, and human health.

Organizer: Sung-JIn Cho (Chungbuk National University)
Chair: Seon-Young Kim (KRIBB), Daehan Lee (Sungkyunkwan University)
16:00-16:30(30') Diving Deep into Giant Panda: the Most Amazing Creatures Ye Wang
(Chengdu Research Base of Giant Panda Breeding)
16:30-17:00(30') Quasi-spatial Single-cell Transcriptome based on Physical Properties Defines Early Aging Associated Niche in Liver Tissue Chuna Kim
(KRIBB)
17:00-17:30(30') Exploring Hematopoietic Pathways via Forward Genetic Screening in Zebrafish Yoonsung Lee
(Kyung Hee University)
16:00-17:30(90')
 

Conference Room 1&2
Satellite Session 4
KOGO Graduate Presentation Session

Chair: Jihwan Park (GIST), Sang Cheol Kim (National Institute of Health)
16:00-16:10(10') Uncovering Genetic Relationships and Shared Etiologies Using Community Detection on GWAS Summaries of 935 Traits from Biobank-scale Datasets Wanson Choi
(Seoul National University College of Medicine)
16:10-16:20(10') Leveraging High-Throughput Proteomics to Identify Tumor-Specific Antigens and Neoantigens for Cancer Treatment Soyeong Kim
(Sookmyung Women's University)
16:20-16:30(10') Association of Tumor-Infiltrating Immune Cells with Patient Survival and Omics Data across Multiple Cancer Types Eun Ah Jeong
(Sookmyung Women's University)
16:30-16:40(10') Tracing Epigenetic Changes in Early Human Embryogenesis Hyein Won
(KAIST)
16:40-16:50(10')
 Ginsenoside Rc Protects Muscles from Oxidative Stress-induced Atrophy by Inhibiting TGF-β Signaling and Nucleolin Expression Seokwon Kim
(Chungnam National University)
16:50-17:00(10') Immunomodulatory Effects of Bojungikki-tang Revealed by Comprehensive Transcriptomic Analysis and Immune Cell Interaction Networks Sang Yun Kim
(Chungnam National University)
17:00-17:10(10') Efficient and Precise Targeting of Cancer Cells using Multiplexed CRISPR/Cas9 Soyoung Lee
(UNIST)
17:10-17:20(10') Epigenetic Signatures of Azacitidine Response Linked to CD8+ T Cell Activity in Myelodysplastic Syndromes Dayoung Kim
(UNIST)
17:20-17:30(10') Partial in vivo Reprogramming Enables Injury-free Intestinal Regeneration Vis Autonomous Ptgs1 Induction Somi Kim
(POSTECH)
2024.09.07. (Sat)
09:00-10:30(90')
 

Hall A
Session 13. Genetic Disease (KOGO-KSMG Joint Session)
From Bench to Bedside: Translational Stratagies for Rare Diseases
 
This session will delve into the critical journey of scientific discoveries from the laboratory to clinical applications, focusing on rare diseases. Our esteemed speakers will share pioneering research, innovative methodologies, and real-world applications that bridge the gap between benchwork and patient care. Join us as we explore the latest advancements, challenges, and future directions in translational research, aiming to improve diagnosis, treatment, and outcomes for individuals with rare diseases.

Organizer: Soo Yeon Kim (Seoul National University)
Chair: Kyong Soo Park (Seoul National University), Hoon Chul Kang (Yonsei University College of Medicine)
09:00-09:20(20') High Throughput Functional Assays to Improve Interpretation of Rare Variants Discovered in Neuromuscular Disease Genes Monkol Lek
(Yale School of Medicine)
09:20-09:40(20') In vitro and vivo Translational Model for a Rare Inherited Metabolic Disease Chong Kun Cheon
(Pusan National University)
09:40-10:00(20') Multiplexed, Multimodal Single Cell Sequencing in PBMC Samples Byungjin Hwang
(Yonsei University College of Medicine)
10:00-10:20(20') Genetic Hearing Loss: from Diagnosis to Treatment Sang-Yeon Lee
(Seoul National University)
09:00-10:30(90')
 

Hall B
Session 14. Proteogenomics
Bridging Genome and Proteome: Proteogenomics Innovations
 
This session will explore the exciting field of proteogenomics, where the integration of genomic and proteomic data is revolutionizing our understanding of biology and disease. Leading experts will discuss cutting-edge methodologies that merge genomic sequencing with protein expression analysis, providing a holistic view of cellular function. Participants will learn about the latest advancements in proteogenomics technologies, including novel analytical tools, computational approaches, and their applications in precision medicine. Attendees will gain insights into how these innovations are driving discoveries in cancer biology, uncovering novel biomarkers, and paving the way for new therapeutic strategies.

Organizer: Hyobin Jeong (Yonsei University)
Chair: Woong-Yang Park (Samsung Medical Center), Kwang Pyo Kim (Kyung Hee University)
09:00-09:20(20') Proteogenomic Characterization of Glioblastoma Evolution Jong Bae Park
(National Cancer Center, Korea)
09:20-09:40(20') Multi-modal Proteome and its Application on Translational Research Kyunggon Kim
(University of Ulsan College of Medicine)
09:40-10:00(20') Proteomic Landscape of Korean Breast Cancer Min-Sik Kim
(DGIST)
10:00-10:20(20') Single-cell Analysis Reveals Dynamic Clonal Evolution and Targetable Phenotypes in Complex Karyotype AML Aino-Maija Leppa
(DKFZ)
09:30-10:15(45')

Conference Room 1&2
Korean Pangenome Project: Recruiting voluntary Korean participants
10:50-11:30(40')
* Plenary Lecture Ⅴ

Chair: Soo Heon Kwak (Peking University)

From Understanding to Modulating the Tumor Microenvironment

Zemin Zhang (Peking University)
11:30-13:00(90')
 

Hall A
Session 15. Immunology
Genomic Immunology and Engineering Immunity
 
The recent success of chimeric antigen receptor T cells (CAR-T cells) in cancer once again demonstrates the clinical potential of immune engineering. Inspired by this success, diverse approaches have been used to boost various aspects of immunity. This session will explore the recent advances in synthetic immune cell engineering and the clinical success of immune cell therapies in various human diseases.

Organizer: Sungho Park (UNIST)
Chair: Tae-Young Roh (Ewha Womans University), Sungho Park (UNIST)
11:30-11:50(20') Latest Developments and Trends in CAR-T Therapy Research Using Advanced Genome Engineering Technologies Hyungseok Seok
(Seoul National University)
11:50-12:10(20') Roles of TET and TDG in DNA Demethylation in the Hematopoietic and Immune Systems Atsushi Onodera
(Chiba University)
12:10-12:30(20') Genetically Modified Macrophages as a Promising Cell Therapy for Inflammatory Bowel Disease Seung Hyeok Seok
(Seoul National University)
12:30-12:50(20') CAR-NK-based Immunotherapy: Advancing the Fight against Solid Tumor Microenvironments Mihue Jang 
(KIST)
11:30-13:00(90')
 

Hall B
Session 16. Cancer (KOGO-KCA Joint Session)
Clinically Actionable Target Discovery for Cancer Care
 
The clinical utility of clinically actionable targets is essential to precision oncology. The session explores cutting-edge genomic research aimed at improving cancer treatment. It includes recent discoveries in the field of clonal hematopoiesis, circulating tumor DNA, and druggable targets on a variety of cancers, including breast, head & neck, and hematologic malignancies. This session provides valuable insights into translating genomic findings into effective cancer therapies, shaping the future of personalized oncology.

Organizer: Han-Byoel Lee (Seoul National University Hospital)
Chair: Sung-Soo Yoon (Seoul National University Hospital), Sung Gwe Ahn (Gangnam Severance Hospital)
11:30-11:50(20') Clonal Hematopoiesis and Cancer: Beyond Simple Clonal Evolution Youngil Koh
(Seoul National University Hospital)
11:50-12:10(20') Clinically Actionable Target Discovery for Cancer Care
: Capturing Oncogenic Drivers in Liquid Biopsy Samples		 Jisun Kim
(University of Ulsan College of Medicine)
12:10-12:30(20') Transcriptomic Profiling of Intermediate Cell Carcinoma of the Liver Hyungoo Woo
(Ajou University)
12:30-12:50(20') Pragmatic Nationwide Master Observational Trial Based on Genomic Alterations in Advanced Solid Tumors: KOSMOS study Soohyeon Lee
(Korea University Anam Hospital)
11:30-13:00(90')
 

Conference Room 1&2
Satellite Session
 

 
     
     
     
     

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