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국제학술대회
Symposia
The 32nd International KOGO Annual Conference
 
Everything Everywhere Genomics
 
 
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2023.10.12(Thu)
09:30-10:50(80')
 

Omnibus Park

 Session 1. Department of Precision Medicine, National Institute of Health
Genetic Predisposition of Complex Diseases in the Korean Population

Organizer: Bong-Jo Kim (National Institute of Health)
Chair: Hyun-Young Park (National Institute of Health)
09:30-09:50(20') Genetic Architecture of Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) So-Young Bang
(Hanyang University Hospital)
09:50-10:10(20') Mendelian randomization to infer causal associations
Hong-Hee Won
(Sungkyunkwan University)
10:10-10:30(20') Genome based risk stratification and prediction of type 2 diabetes Young Jin Kim
(National Institute of Health)
10:30-10:50(20') Development of Cloud-based system for analyzing large-scale genetic data with Korean Genome and Epidemiology Study (KoGES) Sungho Won
(Seoul National University)
09:10-10:20(70')
 

St. Mary's Hall (Songeui Building)

 Session 2. KOBIC
Global Biodata Resources Around the World

Organizer: Seungwoo Hwang (KOBIC)
Chair: Byungwook Lee. Ji-Hwan Park (KOBIC)
09:10-09:30(20')
 The future of data repositories in the context of CBD Masanori Arita
(DNA Data Bank of Japan, National Institute of Genetics)
09:30-09:50(20') The European Nucleotide Archive: database of record, platform for data sharing and data brokering hub
Guy Cochrane
(EMBL European Bioinformatics Institute and Global Biodata Coalition)
09:50-10:10(20') CNCB-NGDC Progress Report
Yiming Bao
(National Genomics Data Center, China National Center for Bioinformation)
10:10-10:20(10') Introduction to Korea BioData Station (K-BDS)
Seungwoo Hwang
(KOBIC)
09:30-11:10(100')
 

Catholic Research Institutes of Medical Science(1002)

 Satellite Session 1
Cancer Proteogenomic for New Paradigm of Cancer Research
Organizer: Joon-Yong An (Korea University)
Chair: Kwang Pyo Kim (Kyunghee University)
09:30-09:55(25') Predicting resistance to immune checkpoint inhibitors through clinically relevant and proteomically expressed features Kwoneel Kim
(Kyunghee University)
09:55-10:20(25') Comprehensive identification of noncanonical MAPs for neoantigen discovery Seung Hyuk Choi
(Hanyang University)
10:25-10:45(25') Proteogenomic Approaches to classify Cholangiocarcinoma Subtypes Jin Young Kim
(Korea Basic Science Institute)
10:45-11:10(25') Lesson from regeneration program to understand lung tumor development Jinwook Choi
(GIST)
11:20-12:00(40')
* Plenary Lecture I
 
Chair: Woong-Yang Park (Sungkyunkwan University) 

Analysis CNVs in cancer and normal tissues with transcriptomics data

Peter Kharchenko

(Harvard Medical School)
12:00-13:00(60')
-------------------
Omnibus Park
Luncheon Seminar 1  DAON BioSciences / XpertGen
12:00-12:30(30')
10x Genomics/DAON BioSciences
Spatial Characterization of Colorectal Cancer Tumor Microenvironment using 10x Xenium

Bo Li

(Genome Institute of Singapore)
12:30-13:00(30')
XpertGen
Science Can’t Wait: Democratizing and decentralizing DNA sequencing with the Element AVITI System
The Element AVITI System: the Next, Next Generation Sequencing

Edwin Hauw
(Element Biosciences)
13:00-14:40(100')
 

Omnibus Park

 Session 3
Single-cell Genomics

Organizer: Jong-Eun Park (KAIST)
Chair: Jongil Kim (Seoul National University)
13:00-13:25(25') Therapy-associated remodeling of pancreatic cancer revealed by single-cell spatial transcriptomics and optimal transport analysis
Martin Hemberg
(Brigham and Women’s Hospital)
13:25-13:50(25') A mouse single cell splicing atlas using Ouro-seq
Jihwan Park
(GIST)
13:50-14:15(25')
Exploring Cellular Mosaics of Skin Disorders:
Unveiling atopic dermatitis and psoriasis through Single-cell RNA sequencing
Seunghee Hong
(Yonsei University)
14:15-14:40(25') Single-cell analysis reveals recurring programs in cancer microenvironment
Jong-Eun Park
(KAIST)
13:00-14:40(100')
 

St. Mary's Hall (Songeui Building)

 Session 4
Sharing Data from COVID19 Infection in Animal Models

Organizer: Je Kyung Seong (Seoul National University; KMPC)
Chair: Ho-Keun Kwon (Yonsei University), Jun Won Park (Kangwon National University)
13:00-13:25(25') Murine COVID-19 lethality is characterized by lymphoid depletion associated with suppressed antigen presenting cell functionality. Jun Won Park
(Kangwon National University)
13:25-13:50(25') Single-cell RNA sequencing of fetal inflammatory course in the lung of COVID-19 infected mouse model Je Kyung Seong
(Seoul National University; KMPC)
13:50-14:15(25') Immune cells are differentially affected by SARS-CoV-2 viral loads in K18-hACE2 mice Heon Yung Gee
(Yonsei University College of Medicine)
14:15-14:40(25') Insights from a Human ACE2-Expressing Mouse Model and Exploration of the Lung-Gut Axis for Enhanced Understanding and Potential Interventions Ho-Keun Kwon
(Yonsei University)
13:00-14:40(100')
 

Catholic Research Institutes of Medical Science(1002)

 Satellite Session 2
Multi-omics Approach to Discover Prognostic Biomarker for Asthma
Organizer: Tae-Bum Kim (Asan Medical Center)
Chair: Tae-Bum Kim (Asan Medical Center)
13:00-13:20(20')

Discovery of Biomarkers based on Multi-Omics analysis in Asthma

 Tae-Bum Kim
(Asan Medical Center)
13:20-13:40(20') Comparative proteomics analysis for plasma and sputum from asthma patients to predict prognosis Kyunggon Kim
(Asan Medical Center)
13:40-14:00(20') Genomic and lifestyle risk estimation of asthma in the UK Biobank Bermseok Oh
(Kyung Hee University)
14:00-14:20(20') Multi-Omics Based Precision Medicine in Asthma Sungho Won
(Seoul National University)
14:20-14:40(20') Deep learning approach to discover gene level biomarkers for Asthma with multiomics data Sun Kim
(Seoul National University)
15:50-17:30(100')
 

Omnibus Park

 Session 5
Exploring the Latest Advances in Epigenetic Gene Regulation: From Chromatin Dynamics to Therapeutic Applications

Organizer: Kyunghwan Kim (Chungbuk National University)
Chair: Daeyoup Lee (KAIST)
15:50-16:15(25') Chromatin dynamics and epigenetic gene regulation Woojin An
(USC)
16:15-16:40(25') Unraveling the SETD1A-SOX2 axis in tamoxifen-resistant breast cancer Kwang Won Jeong
(College of Pharmacy, Gachon University)
16:40-17:05(25') Understanding the Dynamics of DNA high-order structure Ji-Joon Song
(KAIST)
17:05-17:30(25') Spatiotemporal regulation of transcription activation Inwha Baek
(Kyung Hee University)
15:50-17:30(100')
 

St. Mary's Hall (Songeui Building)

 Session 6
Stem Cell Genomics

Organizer: Kihyun Lee (Ewha Womans University, College of Pharmacy)
Chair: Kihyun Lee (Ewha Womans University, College of Pharmacy)
15:50-16:15(25') Single-cell timestamp recording and tracing unravel epigenetic regulation of cell fate decisions Ik Soo Kim
(Gachon University College of Medicine)
16:15-16:40(25') The role of mTOR-S6K1 signal pathway in human brain development Jaecheol Lee
(Sungkyunkwan University, School of Pharmacy)
16:40-17:05(25') Human embryological lineage tracing study using whole genome sequencing. Ji Won Oh
(Yonsei University College of Medicine)
17:05-17:30(25') Iroquois transcription factors: Patterning the molecular heterogeneities of the heart Kyoung-Han Kim
(University of Ottawa)
15:50-17:30(100')
 

Catholic Research Institutes of Medical Science(1002)

 Satellite Session 3
Development of Diagnosis and Therapeutics Technology for Precision Medicine Based on AI Platform and Multi-omics Data Analysis
Organizer: Seongho Ryu (Soonchunhyang University)
Chair: Seongho Ryu (Soonchunhyang University)
15:50-16:15(25') Single-cell omics reveals cellular and molecular factors counteracting HPV-associated clinical benefits in oropharyngeal cancer immunotherapy Insuk Lee
(Yonsei University)
16:15-16:40(25') AI-powered drug discovery and development Hojung Nam
(GIST)
16:40-17:05(25') Systematic analysis of metabolic disease progression Sungwon Jung
(Gachon University College of Medicine)
17:05-17:30(25') AIVariant: a deep learning-based somatic variant detector for highly contaminated tumor samples Dea Hyun Beak
(Seoul National University)
2023.10.13(Fri)
09:00-10:40(100')
 

Omnibus Park

 Session 7
Navigating the Biological Space: Spatial Biology and Analysis to Uncover Novel Insights

Organizer: Hongyoon Choi (Seoul National University Hospital)
Chair: Sangsoo Kim (Soongsil University)
09:00-09:25(25') Navigating the Biological Space: Spatial Biology and Analysis to Uncover Novel Insights Jung U Shin
(Seoul National University College of Medicine)
09:25-09:50(25') Technical advances in Spatial Transcriptomics and FFPE single nucleus RNA seq by Fixative eXchange (FX)-seq Chang Ho Sohn
(Yonsei University)
09:50-10:15(25') Harnessing Spatial Transcriptomics for Evaluation of Molecular Markers related to Drug Distribution Hyung-Jun Im
(Seoul National University)
10:15-10:40(25') Spatial molecular imaging and optimal transport interaction analysis identifies altered intercellular signaling associated with therapeutic resistance in pancreatic cancer Hwang, William L
(Massachusetts General Hospital)
09:00-10:40(100')
 

St. Mary's Hall (Songeui Building)

 Session 8
The First Step in Precision Medicine: The National Pilot Project of Bio Big Data

Organizer: Hyeongmin Kim (KDCA)
Chair: Hyun-Young Park (KDCA)
09:00-09:05(05') Open Greeting  
09:05-09:25(20') Achievement of the National Pilot Project of Bio Big Data and Data Sharing Jung Hyun Lee
(KDCA)
09:25-09:45(20') National Project of Bio Big Data: comprehensive whole genome analysis in rare diseases Beom Hee Lee
(Asan Medical Center)
09:45-10:05(20') Unraveling the somatic genomic landscape of Korean colorectal cancer: Insight from Whole Genome Sequencing Shin Kim
(Keimyung University)
10:05-10:25(20') To be sparse, or not to be, that is the question: Scalable VCF for a biobank-scale WGS project Joon Yong An
(Korea University)
10:25-10:40(15') Q&A  
09:00-10:40(100')

Catholic Research Institutes of Medical Science(1002)
Satellite Session 4. Bertis
Cellular Senescence

Organizer: Myeonghee Yu (Bertis) / Daehee Hwang (Seoul National University)
Chair: Daehee Hwang (Seoul National University)
09:00-09:30(30') RNA homeophagy: a fascinating tiki-taka between protein and RNA metabolism in senescence
Chanhee Kang
(Seoul National University)
09:30-09:50(20') Integrative analysis of cellular senescence
Su Bin Lim
(Ajou University)
09:50-10:10(20')
 Exploring the Human Aging Blood Proteome
Sunghyun Huh
(Bertis)
10:10-10:40(30')
 Changes of nucleocytoplasmic trafficking in cellular senescence
Youngsam Lee
(DGIST)
11:00-11:40(40')
* Plenary Lecture II

 

Chair: Injin Jang (Seoul National University)

Exponentiating Single-cell Genomics

Jimmie Ye
(University of California San Francisco)
11:40-12:20(40')
* Unbong Kang Hyen Sam Award Lecture
 
Chair: Kwang-Lae Hoe (Chungnam National University)

 

Immuno-genomic AI for cancer therapy and diagnosis

Jung Kyoon Choi (KAIST)
12:20-13:20(60')
Luncheon Seminar 2  BMS / Geninus
12:20-12:50(30')
BMS
Single-cell resolution spatial transcriptome construct the brain atlas and evolution

Shiping Liu

(BGI-Research)
12:50-13:20(30')
Geninus
Single Cell RNA Sequencing: 
Powerful technique for improving our understanding of human health

Siyoung Lee

(Geninus Inc.)
13:20-14:00(40')
* Plenary Lecture III
 
Chair: Je Kyung Seong (Seoul National University)

Phenotypic driven approaches to rare disease diagnostics and gene discovery
Damian Smedley
(Queen Mary University of London)
14:10-15:50(100')
 

Omnibus Park

 Session 9
Genetic & Genomic Regulation of Cancer

Organizer: Sung Yup Cho (Seoul National University, College of Medicine), Jae-Seok Roe (Yonsei University)
Chair: Jae-Ho Cheong (Yonsei University)
14:10-14:35(25') Single cell genome-wide screening in primary human T cells Byungjin Hwang
(Yonsei University, College of Medicine)
14:35-15:00(25') Somatic LINE1 retrotransposition in human normal and cancer cells Jenghwan Youk
(Seoul National University, College of Medicine)
15:00-15:25(25') Epigenetic alterations promote pancreatic cancer progression and metastasis Chang-il Hwang
(University of California at DAVIS)
15:25-15:50(25') Unraveling the Significance of Epitranscriptomic Alterations in Cancer Pathogenesis Sung Yup Cho
(Seoul National University, College of Medicine)
14:10-15:50(100')
 

St. Mary's Hall (Songeui Building)

 Session 10
Advances in Omics Technology

Organizer: Planning Committee
Chair: Dong-Sung Lee (University of Seoul)
14:10-14:40(30') Lenovo GOAST: Genomics Optimization and Scalability Tool Dana Alegre (Lenovo)
14:40-15:10(30') Shifting paradigms with PacBio HiFi sequencing
Zuwei Qian
(MDxK Inc. / Pacific Biosciences Inc.)
15:10-15:40(30') Accelerate genomics research in the AWS cloud Hyunmin Kim
(Amazon Web Services (AWS) Korea)
14:10-15:50(100')

Catholic Research Institutes of Medical Science(1002)

 Session 11
Young Scientist Session

Chair: Murim Choi (Seoul National University College of Medicine)
14:10-14:25(15') High-quality genomes reveal divergent RBFOX1 promoters specific to human and vocal learning birds Chul Lee
(The Rockefeller University)
14:25-14:40(15')
 A whole-genome reference panel of 14,393 individuals for East Asian populations accelerates discovery of rare functional variants Jaeyong Choi
(Seoul National University College of Medicine)
14:40-14:55(15') Deciphering the Mechanisms of FOXD2-Mediated Chromatin Remodeling in normal Colon and Cancer Hyo-Min Kim
(Ewha Womans University)
14:55-15:10(15') Intratumoral IL-12 delivery via mesenchymal stem cells combined with PD-1 blockade leads to long-term antitumor immunity in a mouse glioblastoma model Junseong Park
(The Catholic University of Korea)
15:10-15:25(15') Functional RNA Analysis for the Reclassification of Splicing Gene Variants in Hereditary Cancer Hyeji Kim
(National Cancer Center)
15:25-15:40(15') Establishment of patient-derived brain tumor organoids with tumor microenvironment Dokyeong Kim
(The Catholic University of Korea)
16:20-18:00(100')
 

Omnibus Park

 Session 12
Microbial Genomics

Organizer: Woo Jun Sul (Chung-Ang University)
Chair: Woo Jun Sul (Chung-Ang University)
16:20-16:45(25') Microbiome and Virome of the Built Environment Patrick Lee
(City University of Hong Kong)
16:45-17:10(25') The Skin Microbiome in Dermatology Hei Sung Kim
(The Catholic University of Korea)
17:10-17:35(25') Microbiome in chronic respiratory diseases: the characteristics and its therapeutic applications Sei Won Lee
(Asan Medical Center)
17:35-18:00(25') Multi-cagA genotype in Helicobacter pylori Jeong Heon Cha
(Yonsei University College of Dentistry)
16:20-18:00(100')
 

St. Mary's Hall (Songeui Building)

 Session 13
Bioinformatics and Systems Biology

Organizer: Sangwoo Kim (Yonsei University)
Chair: Yeun-Jun Chung (The Catholic University of Korea)
14:10-14:35(25') Comprehensive analysis of neoantigens derived from structural variation across whole genomes from 2528 tumors Ruibin Xi
(Peking University)
14:35-15:00(25') Genetic makeup underlying anti-cancer drug response Jinhyuk Bhin
(Yonsei Univ. College of Medicine)
15:00-15:25(25') Long-read translatome analysis reveals cis-regulatory factors controlling poly(A) tail–translation coupling Hyeshik Chang
(Seoul National University)
15:25-15:50(25') RAMP: response-aware multi-task learning with contrastive regularization for cancer drug response prediction Semin Lee
(UNIST)
16:20-18:00(100')

Catholic Research Institutes of Medical Science(1002)

 Session 14
KOGO Graduate Presentation Session

Chair: Won-Ki Cho (KAIST)
16:20-16:30(10') A streamlined pipeline based on HmmUFOtu for microbial community profiling using 16S rRNA amplicon sequencing Hyeonwoo Kim
(Soongsil University)
16:30-16:40(10') Causal Association of Type 2 Diabetes and Pulmonary Tuberculosis: A Mendelian Randomization Study Hyunsuk Lee
(Seoul National University)
16:40-16:50(10') Increased inflammatory signature in myeloid cells in non-small cell lung cancer patients with high clonal hematopoiesis burden Hyungtai Sim
(Seoul National University College of Medicine)
16:50-17:00(10') Epigenetic Landscape Analysis Reveals Predictive Insights into Imatinib Resistance in Chronic Myeloid Leukemia Dayoung Kim
(UNIST)
17:00-17:10(10') Single-cell RNA sequencing reveals novel adipose iNKT cell subpopulations controlling adipocyte turnover by orchestrating cellular crosstalk. Eun Seo Park
(DGIST)
17:10-17:20(10') Genotype refinement of de novo variants from whole-genome dataset provides an accurate insight into the Korean population with rare diseases Namwon Kim
(KRIBB)
17:20-17:30(10') Comprehensive benchmarking of variant calling on X chromosome from large-scale whole genome sequencing data Ganghee Lee
(Korea University)
17:30-17:40(10') Chromosome-level genome assembly of chub mackerel (Scomber japonicus) migrating in the Indo-Pacific Ocean Young Ho Lee
(Seoul National University)
17:40-17:50(10')
 Highly accurate Korean draft genomes reveal structural variation highlighting human telomere evolution Gunwoo Park
(KRIBB)
17:50-18:00(10') Application of multi-omics to reveal trajectory of transcriptomic changes in human development and aging Yunah Lee
(KAIST)
2023.10.14(Sat)
09:00-10:15(75')
 

St. Mary's Hall (Songeui Building)

 Session 15. KOGO-KSMG Joint Session
Precision Diagnosis and Treatment Strategies for Rare Human Diseases Using Advanced Genetic Technologies

Organizer: Jungmin Ko (Seoul National University Hospital)
Chair: Murim Choi (Seoul National University College of Medicine)
09:00-09:25(25') In vivo Genome Editing for Vision Jeong Hun Kim
(Seoul National University College of Medicine)
09:25-09:50(25') Towards creating an atlas of inflammatory skin diseases using scRNAseq and Spatial transcriptomics Hyunje kim
(Seoul National University College of Medicine)
09:50-10:15(25') Genomic and transcriptomic profiling reveal molecular characteristics of parathyroid carcinoma Sangwoo Kim
(Yonsei University)
10:15-10:55(40')
Plenary Lecture IV
 
Chair: Sung-Soo Yoon (Seoul National University College of Medicine)

Genomic approaches to improving rare disease discovery
Anne O'Donnell Luria
(Harvard Medical School)
11:15-11:55(40')
Plenary Lecture V
 
Chair: Sanghyuk Lee (Ewha Womans University)

Two decades of human structural genomic variation
Charles Lee
(The Jackson Laboratory for Genomic Medicine)
13:00-14:15(75')
 

St. Mary's Hall (Songeui Building)
Session 16. KOGO-KCA Joint Session
Cancer Genomics - Application of Genomics for Translational Cancer Research

Organizer: Tae Min Kim (Seoul National University Hospital)
Chair: Tae Min Kim (Seoul National University Hospital)
13:00-13:25(25')

Convergence of Plasticity Phenotypes Revealed Through Single Cell Analysis of Mouse and Human Prostate Cancer

 Jungmin Choi
(Korea University)
13:25-13:50(25') Precision Oncology at SMC: make every data usable for future cancer medicine Minae An
(Samsung Medical Center)
13:50-14:15(25') Comprehensive genomic characterization of Korea advanced pan-cancer patients factilitates personalized treatment Kyungha Sa
(Korea University)
14:30-16:10(100')
 

St. Mary's Hall (Songeui Building)

 Session 17
Complex Disease Genomics: Immune-mediated inflammatory disease

Organizer: Tae-Gyun Kim (Yonsei University College of Medicine)
Chair: Eun Young Lee (Seoul National University Hospital)
14:30-14:55(20') Unraveling the Intervenome:
Investigating Drug Effects on Single-Cell Transcriptomes in Complex Genetic Diseases		 Jeong Seok Lee 
(KAIST)
14:55-15:20(20') Towards a cell-type-specific understanding of complex diseases Boxiang Liu
(National University of Singapore)
15:20-15:45(20') Analysis of drug reactivity in drug-induced hypersensitivity syndrome: single-cell RNA-sequencing Do-Young Kim
(Yonsei University College of Medicine)
15:45-16:10(30') Single cell and spatial omics for neuroinflammation of Alzheimer’s disease and its diagnostic translation Hongyoon Choi
(Seoul National University Hospital)

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