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Symposia

The 30th KOGO Annual Conference

¢ºÀϽà : 2021³â 9¿ù 6ÀÏ(¿ù) ~ 9¿ù 7ÀÏ(È­)
¢ºÀå¼Ò : Virtual Symposium

* ¼¼¼Ç¸íÀ» Ŭ¸¯ÇϽøé ÇØ´ç³í¹®À» º¸½Ç ¼ö ÀÖ½À´Ï´Ù.
2021.09.06(¿ù)
09:00-10:40(100')
 

Hall A

Session 1. Single cell genomics

Organizer: ÁÖ¿µ¼®(KAIST)
Chair: ¿ÀÁö¿ø(°æºÏ´ëÇб³ ÀÇ°ú´ëÇÐ)

09:00-09:25(25') Identification of somatic mutations in single cell whole-genome sequencing data Peter Park(Harvard Medical School
(US))
09:25-09:50(25') Clonal dynamics in early human embryogenesis inferred from somatic mutation ÁÖ¿µ¼®
(KAIST)
09:50-10:15(25') High-resolution CRISPR lineage tracing in model systems Aaron McKenna(Dartmouth Geisel School of Medicine
(US))
10:15-10:40(25') The mutational landscape of human somatic and germline cells Raheleh Rahbari(Wellcome Sanger Institute
(UK))
09:00-10:40(100')
 

Hall B

Session 2. Medical genomics

Organizer: °í¿µÀÏ(¼­¿ï´ëÇб³)
Chair: À̽ÂÇ¥(¼­¿ï´ëº´¿ø)

09:00-09:25(25') Clonal hematopoiesis and epigenetic aging Siddhartha Jaiswal(Stanford University)
09:25-09:50(25') Inherited and acquired genetic contributions to atherosclerotic cardiovascular disease (ASCVD) ¼ÛÇÑ
(Genome Opinion)
09:50-10:15(25') Genetic Testing in The Age of Genomic Medicine ±è¸¸Áø
(¼­¿ï´ëº´¿ø)
10:15-10:40(25') Rare variant analysis in cancer °í¿µÀÏ
(¼­¿ï´ëº´¿ø)
11:00-11:40(40') * Plenary Lecture I

Principles of Epigenetics and Chromatin in Development and Human Disease

Chair: ÀåÀÎÁø(¼­¿ï´ëÇб³)
Ali Shilatifard(Northwestern University)

11:40-12:40(60')
 

Hall A

Session 3. Advances in omics technology
Organizer: Çѱ¹À¯ÀüüÇÐȸ ±âȹÀ§¿øȸ
Chair: À¯°æÇö(¼÷¸í¿©ÀÚ´ëÇб³)
±èÇö¼®(¿¬¼¼´ëÇб³)
11:40-12:10(30')

Estimation of Tumor Mutation Burden in Circulating Tumor DNAs

À̽ÂÅÂ(¿¬¼¼´ëÇб³ ÀÇ°ú´ëÇÐ)
12:10-12:40(30') Single Cell : Powerful technique for improving our understanding of human health
À̽ÿµ(Áö´Ï³Ê½º)
11:40-12:40(60')
 

Hall B

Session 4. KOBIC-KISTI, The National Genome Project

Organizer: ±è¼±¿µ(KOBIC)
Chair: ±è¼±¿µ(KOBIC)

11:40-12:00(20') Introduction to The National Genome Project ¹ÚÁöȯ
(KOBIC)
12:00-12:20(20') Overview of the data processing pipeline for the National Genome Project ±è»ó¿Á
(KOBIC)
12:20-12:40(20') Research environment platform for biomedical big data analysis and research °­È¿Áø
(KISTI)
13:40-15:20(100')
 

Hall A

Session 5. Viral Genomics

Organizer: ¹Ú¸¸¼º(°í·Á´ëÇб³)
Chair: ¹Ú¸¸¼º(°í·Á´ëÇб³)

13:40-14:05(25') European COVID-19 resurgence foretold: untangling persistence and introductions in SARS-CoV-2 spread. Philippe Lemey
(Katholieke Universiteit Leuven)
14:05-14:30(25') Multiple reassortants of H5N8 clade2.3.4.4b highly pathogenic avain influenza viruses detected in Korea ÀÌÀ±Á¤
(³ó¸²Ãà»ê°Ë¿ªº»ºÎ)
14:30-14:55(25') Automatic network-based taxonomic classifier for prokaryotic virus genomes ÀåÈ£ºó
(°í·Á´ëÇб³ ÀÇ°ú´ëÇÐ)
14:55-15:20(25') Genomic epidemiology and Novel Virus Discovery of Zoonotic Viruses Using Next-Generation Sequencing ±è¿ø±Ù
(ÇѸ²´ëÇб³ ÀÇ°ú´ëÇÐ)
13:40-15:20(100')
 

Hall B

Session 6. Plant genomics and Evolution

Organizer: ±è»ó±Ô(KAIST)
Chair: ±è»ó±Ô(KAIST)

13:40-14:05(25') Whole-genome resequencing reveals genomic adaptations in a facultatively asexual weed Shuqing Xu
(University of Münster)
14:05-14:30(25') The First Genomic Selection of Korean Red Pine (Pinus densiflora) Trees ½Éµ¿È¯
(Ãæ³²´ëÇб³)
14:30-14:55(25') Optimization of productivity by manipulating of genetic gene dosage in hexaploid orphan crop ¹Ú¼øÁÖ
(¿ø±¤´ëÇб³)
14:55-15:20(25') Natural variation and CRISPR-mediated genome editing to study evolutionary adaptation. ±è»óÅÂ
(°¡Å縯´ëÇб³)
15:40-17:20(100')
 

Hall A

Session 7. Epigenomics

Organizer: À̴뿱(KAIST) Chair: ±è¹Ì¿µ(KAIST)

15:40-16:05(25')     Histone Variants and Their Impact on Epigenetic Regulation Laura Banaszynski
(UTSW, USA)
16:05-16:30(25')     Roles of epigenetic regulators in hypothalamic neuron development À̽ÂÈñ
(¼­¿ï´ëÇб³)
 
    16:30-16:55(25')                            
Histone sumoylation and chromatin dynamics: histone sumoylation promotes Set3 histone-deacetylase complex-mediated transcriptional regulation ·ùÈ«¿­
(°æºÏ´ëÇб³)
16:55-17:20(25')   Telomeres reforged with non-telomeric sequences ±èõ¾Æ
(Çѱ¹»ý¸í°øÇבּ¸¿ø)
15:40-17:20(100')
 

Hall B

Session 8. Clinical Pharmacogenomics Service in Korea

Organizer: ¹Ú½Çºñ¾Æ(¼­¿ï¼º¸ðº´¿ø Ç÷¾×º´¿ø)
Chair: ¾È¸íÁÖ(»ï¼º¼­¿ïº´¿ø Ç÷¾×Á¾¾ç³»°ú)

15:40-16:05(25') Genetic predisposition and leukemic evolution in adult myeloid neoplasms. Hideki Makishima
(Department of Pathology and Tumor Biology, Kyoto University)
16:05-16:30(25') Prediction of treatment response to PD-1 blockade in cancer patients ½ÅÇö¹«
(¼­¿ï´ëÇб³ ÀÇ°úÇаú)
16:30-16:55(25') Extrachromosomal DNA elements are frequent in tumors and can contribute to tumor heterogeneity. ±èÈÆ
(¼º±Õ°ü´ëÇб³ ¾àÇдëÇÐ)
16:55-17:20(25') Multigene Assays for Hormone Receptor-positive, HER2-negative Breast Cancer ÀÌÇѺ°
(¼­¿ï´ëÇб³º´¿ø ¿Ü°ú)
2021.09.07(È­)
09:00-10:40(100')
 

Hall A

Session 9. Immuno-Genomics in Cancer Immunotherapy Era

Organizer: ³ëÅ¿µ(Æ÷Ç×°ø°ú´ëÇб³)
Chair: ¹Ú¸¸¼º(°í·Á´ëÇб³)

09:00-09:20(20')
Tumor and immune cell determinants of immunotherapy response in human lung cancer
Kurt Schalper
(Yale University)
09:20-09:40(20') RORa enforces stability of the T-helper-17 cell effector program ÀÌÁØ¿ë
(¿¬¼¼´ëÇб³ ÀÇ°ú´ëÇÐ)
09:40-10:00(20') Spatial transcriptome of gastric cancers ±èŹÎ
(°¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ)
10:00-10:20(20') Immunological Landscape of Virus Infection-Driven TB Pathogenesis ÇÏ»óÁØ
(¿¬¼¼´ëÇб³)
10:20-10:40(20') Integrative Transcriptome Profiling Reveals SKA3 as a Novel Prognostic Marker in Non-Muscle Invasive Bladder Cancer °­±ÔÈ£
(ÃæºÏ´ëÇб³)
09:00-10:40(100')
 

Hall B

Session 10. Microbiome and Disease

Organizer: ÀÌÀºÁø(°í·Á´ëÇб³)
Chair: ÀÌÁ¤½Å(°­¿ø´ëÇб³)

09:00-09:25(25') Mining Metabolites from Microbiota Sungwhan Oh
(Harvard University)
09:25-09:50(25') Microbial metabolites in metabolic diseases and drug responses °í¾Æ¶ó
(POSTECH)
09:50-10:15(25') What Makes Animal Gut Microbiome Changed? ±èÀº¹è
(°­¿ø´ëÇб³)
10:15-10:40(25') Multiple uORFs-mediated Control of a Virulence Factor of Intracellular Pathogens during Infection ÀÌÀºÁø
(°í·Á´ëÇб³)
11:00-11:40(40') * Plenary Lecture II

Interpreting Disease Risk Variants with Single-cell Epigenomics

Chair: Ç㱤·¡(Ãæ³²´ëÇб³)
Bing Ren(University of California San Diego)

11:40-12:20(40')
* Unbong Kang Hyen Sam award lecture

Chair: ±è¿µÁØ(¿¬¼¼´ëÇб³)

Single cell profiling of tumor microenvironment                                       ¹Ú¿õ¾ç(¼º±Õ°ü´ëÇб³)
12:20-13:20(60')
Special session on chronic kidney disease

Organizer: ¹ÚÁ¾ÈÆ(¼÷¸í¿©ÀÚ´ëÇб³)
Chair: ¹ÚÁ¾ÈÆ(¼÷¸í¿©ÀÚ´ëÇб³)

12:20-12:50(30') Genetics of autosomal dominant polycystic kidney disease: an update

York Pei(University of Toronto)

12:50-13:20(30') Systems biology approaches implicate dysregulated cellular metabolism in the pathobiology of polycystic kidney disease Gregory G. Germino( National Institutes of Health (NIH))
13:20-15:00(100')
 

Hall A

Session 11. Genomics and Multiomics Approaches to Complex Disease/Traits

Organizer: ¼ºÁÖÇå(¼­¿ï´ëÇб³)
Chair: ¼ºÁÖÇå(¼­¿ï´ëÇб³)

13:20-13:45(25') Discovering the deep networks that define the complex architecture of human personality Igor Zwir
(Washington University St. Louise)
13:45-14:10(25') Neuroimaging genetics in Alzheimer’s disease Kwangsik Nho
(Indiana University)
14:10-14:35(25') Segregation analysis of population-based breast cancer families: implications for breast cancer genetic susceptibility and risk prediction Shuai Li
(University of Melbourne)
14:35-15:00(25') Leveraging Genomics to Dissect Heterogeneity of Type 2 Diabetes Miriam S. Uder
(Massachusetts General Hospital)
13:20-15:00(100')
 

Hall B

Session 12. New Technologies in Genomics

Organizer: ÃÖ¹«¸²(¼­¿ï´ëÇб³)
Chair: ÃÖ¹«¸²(¼­¿ï´ëÇб³)

13:20-13:40(20') Low-pass sequencing increases the power of GWAS and decreases measurement error of polygenic risk scores compared to genotyping arrays Jeremy Li
(GenCove)
13:40-14:00(20') Application of optical genome mapping for detection and characterization of constitutional and somatic structural variations ½Å»õ¾Ï
(¿¬¼¼´ëÇб³ ¼¼ºê¶õ½ºº´¿ø)
14:00-14:20(20') Long-read sequencing and de novo genome assemblies reveal complex chromosome end structures caused by telomere dysfunction at the single nucleotide level ±èÁØ
(¼­¿ï´ëÇб³)
14:20-14:40(20') Deciphering Landscape of Early Esophageal Squamous Carcinogenesis through Single-Cell/Nucleus RNA Sequencing and Spatial Transcriptomics ÃÖÁ¤¹Î
(°í·Á´ëÇб³ ÀÇ°ú´ëÇÐ)
14:40-15:00(20') Spatial transcriptomics analysis on tumor microenvironment ¹Úµ¿Çö
(Áö´Ï³Ê½º)
15:20-17:00(100')
 

Hall A

Session 13. Non-coding RNAs and Epitranscriptomes

Organizer: ÇÑÁøÁÖ(KAIST)
Chair: ÇÑÁøÁÖ(KAIST)

15:20-15:45(25') Molecular mechanisms of gene expression regulation by m6A mRNA modification ÃÖÁØÈ£
(ÇѾç´ëÇб³)
15:45-16:10(25') The SARS-CoV-2 RNA interactome ÀÌ¿µ¼®
(KAIST)
16:10-16:35(25') The role of immune activation by mitochondrial double-stranded RNAs in degenerative diseases ±èÀ¯½Ä
(KAIST)/td>
16:35-17:00(25') Existence, profiling, and function of mature microRNA-binding proteins Je-Hyun Yoon
(Medical University of South Carolina, USA)
15:20-17:00(100')
 

Hall B

Session 14. Bioinformatics in omics data analysis

Organizer: ÃÖ¼±½É(°­¿ø´ëÇб³)
Chair: ³²Áø¿ì(ÇѾç´ëÇб³)

15:20-15:45(25') Expression variability, Cellular plasticity, and Cancer Sridhar Hannenhalli(National Institutes of Health (NIH))
15:45-16:10(25') Network biology approaches to understand patients’ response to cancer treatments ±è»ó¿í
(Æ÷Ç×°ø°ú´ëÇб³)
16:10-16:35(25') Detection of enhancer hijacking of oncogenes via IGH rearrangments ³²Áø¿ì
(ÇѾç´ëÇб³)
16:35-17:00(25') Analysis of antisense transcripts expressed in Korean colorectal cancer ÃÖ¼±½É
(°­¿ø´ëÇб³)

Çѱ¹À¯ÀüüÇÐȸ, [04501] ¼­¿ïƯº°½Ã Áß±¸ ¸¸¸®Àç·Î 193, 806È£(¸¸¸®µ¿1°¡, µð¿Àºô)
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